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This may produce more consistent fat mobilisation throughout the day

Voluntary reporting systems are subject to confirmation bias (patients and clinicians attribute new symptoms to a recently started medication)

Winfrey told the outlet that she once though taking a weight-loss drug would be "the easy way out." But she later realized "the fact that there's a medically approved prescription for managing weight and staying healthier, in my lifetime, feels like relief, like redemption, like a gift, and not something to hide behind and once again be ridiculed for," she said

A lot of people use them for increasing energy, which might then indirectly contribute to better physical activity and help them with their weight loss